This is our best antioxidant mix, perfect for use with all our bases. We highly recommend this product.
Ingredients: Pomegranate (Punica granatum) seed oil, rosehip (Rosa affinis rubiginosa) seed oil, alpha-D-tocopherol (vitamin E), lycopene, tocotrienols, astaxanthin, lutein, alpha lipoic acid, ascorbyl palmitate.
Further information: The requirement for vitamin E was detected when researchers found that unless it was present in the diet, pregnancy (in laboratory rats) could not be completed. Indeed, the name "tocopherol" derives from the Greek words for childbirth (tos), and to bring forth (phero). Vitamin E serves as a scavenger for free radicals that are destructive to the cell membrane, whose integrity is paramount to cell metabolism and life.
Although alpha-D-tocopherol is the most widespread vitamin E, other tocols are also vitamin E, in the sense that they have vitamin E activity. The only difference between tocotrienols and tocopherol is that tocotrienols have three double bonds in their side chain and have a higher antioxidant activity.
Astaxanthin is a carotenoid, i.e. a carotene-like chemical. Carotenoids, and especially astaxanthin, protect cells against oxidation by 1) quenching singlet oxygen and dissipating the energy as heat and 2) scavenging free radicals to prevent and terminate chain reactions. Due to its particular molecular structure, astaxanthin serves as an extremely powerful antioxidant. It has a very effective quenching effect against singlet oxygen, a powerful scavenging ability for lipid and free radicals and effectively breaks peroxide chain reactions Carotenoids are effective at low oxygen concentrations, complementing the activity of vitamin E which is effective at higher oxygen concentrations. Natural astaxanthin has been shown to be a potent antioxidant over 500 times stronger than vitamin E and 10 times stronger than beta-carotene. Astaxanthin has also been shown to enhance and modulate the immune system. These effects in combination or separately may reduce the acute inflammation reaction of the skin and tissue just beneath the skin that follows excessive exposure to UV radiation.
Lycopene: This carotenoid is the key antioxidant in tomato, Lycopersicon esculentum, and responsible for the many health benefits of tomato (tomato eaters have lower risk of several types of cancer). Lycopene traps singlet oxygen, making it a great antioxidant, but that is not all of it. At physiological concentrations it inhibits cell growth of some human cancers without toxic effects on normal cells, apparently by upregulating a gene, connexin 43, that restores cells to normal proliferation. The combination of lycopene and lutein synergistically interact as antioxidants, and this may relate to specific positioning of different carotenoids in membranes.
Lutein slows down cell aging, oxidative damage by UV-B irradiation, expression of matrix metalloproteinases and production of interleukins.
Alpha lipoic acid: ALA is a naturally occurring dithiol (--SH) complex, and is the prosthetic (i.e. non-proteic) group of several very important enzymes, including the transacetylase part of the enzyme complex that catalyzes the decarboxylation of pyruvate so that the remaining 2-carbon group can enter the Krebs cycle. Aside from its enzymic role, in vitro and in vivo studies suggest that ALA also acts as a powerful micronutrient with diverse pharmacologic and antioxidant properties.
References:
Weber, Christine; Podda, Maurizio; Rallis, Michalis; Thiele, Jens J.; Traber, Maret G.; Packer, Lester. (1997) Efficacy of topically applied tocopherols and tocotrienols in protection of murine skin from oxidative damage induced by UV-irradiation. Free Radical Biology & Medicine, 22(5), 761-769.
Trevithick, JR, Xiong H, Lee S. (1992) Topical tocopherol acetate reduces post-UVB sunburn associated erythema, edema and skin sensitivity in hairless mice. Arch Biochem Biophys 296: 575.
Kiyose, Chikako; Ueda, Tadahiko (2004) Distribution and metabolism of tocopherols and tocotrienols in vivo. Journal of Clinical Biochemistry and Nutrition, 35(1), 47-52
Seki, Taisuke; Sueki, Hirohiko; Kohno, Hiromi; Suganuma, Kaoru; Yamashita, Eiji (2001) Effects of astaxanthin from Haematococcus pluvialis on human skin. Patch testing, skin repeated application test, effect on wrinkle reduction. Fragrance Journal : 29(12), 98-103.
Savoure, Nicole; Briand, Gilberte; Amory-Touz, Marie-Christine; Combre, Alain; Maudet, Maryvonne; Nicol, Marc (1995) Vitamin A status and metabolism of cutaneous polyamines in the hairless mouse after UV irradiation: action of beta-carotene and astaxanthin. International Journal for Vitamin and Nutrition Research: 65(2), 79-86.
http://en.wikipedia.org/wiki/Astaxanthin
http://www.cyanotech.com/pdfs/bioastin/axbul62.PDF
Most of our items can be mixed together. Please let us know if you have questions regarding specific combinations.

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