Niacinamide by Skinactives

Niacinamide

$8.50 / 5gm.

Active ingredient in Hylexin

Niacinamide (nicotinamide for chemists) is part of coenzymes essential for metabolism. Because we cannot make it, we must acquire niacinamide from outside sources, making it by definition, a vitamin.

Even if we obtain enough niacinamide through food and multivitamin supplements, application of niacinamide topically is beneficial. As skin ages, the body no longer supplies enough nutrients to the skin, partly because the density of blood vessels reaching the dermis decreases. Also, application of niacinamide topically has been shown to benefit skin color, decrease melanin synthesis (important for hyperpigmentation), decrease inflammation and pruritus (itching).

Properties: Use for: atopic dermatitis, itching, sebum control, skin lightening

Use: add one teaspoon to 4 oz. of cream or lotion and mix. The powder will dissolve very quickly.

Further Information:

The biochemical effects of niacinamide include increased concentration of NADPH, the donor of reducing power in cell biosynthesis, an effect that translated in incraesed synthesis of collagen, involucrin, filaggrin, and keratin. Topical application of niacinamide also decreased UV-induced skin cancers and prevented immunosuppression by UV irradiation.

The effect of niacinamide on inflammation is through inhibition of histamine release by mast cells, neutrophil chemotaxis, and release of inflammatory mediators.

Niacinamide will also help with skin infections in diabetics. Please note that application of niacinamide is contra-indicated for people affected by Parkinson disease.

References:

Hakozaki T; Minwalla L; Zhuang J; Chhoa M; Matsubara A; Miyamoto K; Greatens A; Hillebrand G G; Bissett D L; Boissy RE (2002) The effect of niacinamide on reducing cutaneous pigmentation and suppression of melanosome transfer. The British journal of dermatology 147(1): 20-31.

Soma, Yoshinao; Kashima, Masato; Imaizumi, Akiko; Takahama, Hideto; Kawakami, Tamihiro; Mizoguchi, Masako. (2005) Moisturizing effects of topical nicotinamide on atopic dry skin. International Journal of Dermatology,44(3): 197-202.

Gensler, Helen L. (1997) Prevention of photoimmunosuppression and photocarcinogenesis by topical nicotinamide. Nutrition and Cancer (1997), 29(2), 157-162.

Each tube is enough for about 32 oz of cream or lotion and can be combined with our other actives. Use in your favourite cream or purchase our Canvas base cream or Sea Kelp bioferment (sea kelp is perfect for people with oily skin).

anti-age, anti-itch, anti-acne, skin lightener

These claims have not been approved by the FDA and these products are not intended to diagnose, cure, or treat any disease.

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