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Quercetin

Quercetin

5 gm$7.50
 

Quercetin inhibits fibroblast proliferation, spurs collagen production, and contraction of keloid and hypertrophic scar-derived fibroblasts.

It can help prevent the release of histamine and other mediators of allergic reactions, possibly by stabilizing cell membranes so that they are less reactive to allergens.

Quercetin also exhibits anti-inflammatory properties, inhibiting formation of inflammatory prostaglandins and leukotrienes. In vitro and animal studies have shown that Quercetin inhibits degranulation of mast cells, basophils and neutrophils. Such activity could account, in part, for Quercetin's anti-inflammatory, anti-allergy, and immunomodulating activities.

Usage

Each tube is enough for 20 fl oz of cream or lotion at just under 1% concentration (5 g in 600 mL cream). Use in your favorite cream or add to our Canvas Base Cream or a Sea Kelp Bioferment base. The powder will not dissolve immediately but will release components slowly into the cream/lotion.

Further Info

Quercetin is a favonoid (same type of compound as in Green Tea EGCG and Rutin) and is a natural chemical present in onion.

In vitro and animal studies suggest that Quercetin inhibits tyrosine kinase and nitric oxide synthase and that it modulates the activity of the inflammatory mediator, NF-kappaB. The mechanisms of anti-viral (in some cases enhanced with vitamin C) and anti-cancer activity that have been observed, again in in vitro and in animal studies, are unknown.

Another interesting property of Quercetin is its anti-elastase activity, meaning it inhibits the activity of the endogenous enzyme responsible for the breakdown of elastin, a component crucial to skin elasticity.

Reference

Phan, T.-T.; Lim, Ivor J.; Chan, S.-Y.; Tan, E.-K.; Lee, S.-T.; Longaker, M. T (2004), Suppression of transforming growth factor beta/Smad signaling in keloid-derived fibroblasts by quercetin: Implications for the treatment of excessive scars. Journal of Trauma: Injury, Infection, and Critical Care 57(5), 1032-1037. Phan, T. T.; Lim, I. J.; Sun, L.; Chan, S. Y.; Bay, B. H.; Tan, E. K.; Lee, S. T. (2003) Quercetin inhibits fibronectin production by keloid-derived fibroblasts. implication for the treatment of excessive scars. Journal of Dermatological Science, 33(3), 192-194. Skaper, S.D.; Fabris, M.; Ferrari, V.; Dalle Carbonare, M.; Leon, A. Quercetin protects cutaneous tissue-associated cell types including sensory neurons from oxidative stress induced by glutathione depletion: cooperative effects of ascorbic acid. Free Radical Biology & Medicine (1997), 22(4), 669-678.

 
These claims have not been approved by the FDA and these products are not intended to diagnose, cure, or treat any disease.
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