Found in red wine. It seems that resveratrol (3,5,4'-trihydroxystilbene), a polyphenolic antioxidant found in grapes and red wine, blocks UVB-mediated activation of the factor NFkappa-B,and this would be the mechanism of protection against photocarcinogenesis. Resveratrol could be useful in the treatment of skin conditions, including fungal infection and diabetic wounds.
Our Resveratrol comes from Polygonum cuspidatum, Japanese knotweed. A plant that produces Resveratrol in very high concentrations.
Additional information suggests that Resveratrol may mimic the beneficial effects of a low calorie diet. See http://www.nytimes.com/2006/11/02/science/02drug.html for the New York Times' coverage.
We use Resveratrol in our anti-age cream. Please click for more information on this ready to use product.
Our new high purity Resveratrol disslves better and leaves creams feeling smoother and with a lighter color.
References:
The new York Times has an extensive piece on Resveratrol:
http://www.nytimes.com/2006/11/02/science/02drug.html
Adhami, V.M. ; Afaq, F.; Ahmad, N. (2003) Suppression of ultraviolet B exposure-mediated activation of NF-?B in normal human keratinocytes by resveratrol. Neoplasia, 5:74-8
Wolter, F.; Stein, J. (2002) Biological activities of resveratrol and its analogs. Drugs of the Future, 27: 949-959.
Bernard, P.; Berthon, J.-Y.(2000) Resveratrol: An original mechanism on tyrosinase inhibition International Journal of Cosmetic Science 22: 219-224.
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