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Regenerating Defensin Serum

$54.99

Harness the celebrated renewing and regenerating effects of honey and royal jelly with a groundbreaking serum inspired by nature’s sweetest active. To achieve a never-before-seen intensity of skin renewal, we pioneered a world-exclusive protein, available for the first time ever in this revolutionary new serum: Honey Bee Defensin-1. The same natural defensin that gives honey and Royal jelly some of their beneficial properties, Honey Bee Defensin-1 mobilizes skin keratinocytes, elevating natural mechanisms for reversing damage loss of structure.

Powered by this innovative ingredient and its unique combination with growth factors and lipids, Regenerating Defensin Serum helps protect, restore, and rejuvenate skin. Perfect for sensitive skin, with a honey-colored lush texture; and wide array of antioxidants, Regenerating Defensin Serum offers what only the most advanced science can deliver: regenerated skin that is healthier and more resilient than ever. 

Each Skin Actives Regenerating Defensin Serum bottle contains the defensin equivalent of over half an ounce of royal jelly. This serum is the perfect way to introduce the benefits of royal jelly into a skincare routine and is also the first bee defensin product available for users looking for a vegan product and one free from bee and honey allergens.

Harness the celebrated renewing and regenerating effects of honey and royal jelly with a groundbreaking serum inspired by nature’s sweetest active. To achieve a never-before-seen intensity of skin renewal, we pioneered a world-exclusive protein, available for the first time ever in this revolutionary new serum: Honey Bee Defensin-1. The same natural defensin that gives honey and Royal jelly some of their beneficial properties, Honey Bee Defensin-1 mobilizes skin keratinocytes, elevating natural mechanisms for reversing damage loss of structure.

Powered by this innovative ingredient and its unique combination with growth factors and lipids, Regenerating Defensin Serum helps protect, restore, and rejuvenate skin. Perfect for sensitive skin, with a honey-colored lush texture; and wide array of antioxidants, Regenerating Defensin Serum offers what only the most advanced science can deliver: regenerated skin that is healthier and more resilient than ever. 

Each Skin Actives Regenerating Defensin Serum bottle contains the defensin equivalent of over half an ounce of royal jelly. This serum is the perfect way to introduce the benefits of royal jelly into a skincare routine and is also the first bee defensin product available for users looking for a vegan product and one free from bee and honey allergens.

How it works

  • Renew and regenerate skin
  • Leaves skin softer, smoother and healthier looking
  • Vegan and can be used on people with bee and honey allergies

How to use it

Apply to face, neck and decolletage once or twice daily.

Quick Tips


Ingredients

Water, Glycerin, Lactobacillus/Lactococcus/Leuconostoc/Saccharomyces Laminaria Digitata Ferment Filtrate (and) Algin, Rosa Canina (Rosehip) Seed Oil, Simmondsia Chinensis (Jojoba) Oil, sr-Honey Bee Defensin-1 , sh-Oligopeptide-1, Olea Europaea (Olive) Leaf Extract, Quercetin, Aloe Barbadensis Leaf Extract, Fucoidan, Oryzanol, Hippophae Rhamnoides (Seabuckthorn) Fruit Oil, Dimethicone, Caprylic/Capric Triglyceride, Polyacrylate Crosspolymer-6, Pentylene Glycol, Sucrose Laurate, Propanediol, Ethylhexylglycerin, Benzoic Acid

Research

Bílikova K, Huang SC, Lin IP, Šimuth J, Peng CC. (2015) Structure and antimicrobial activity relationship of royalisin, an antimicrobial peptide from royal jelly of Apis mellifera. Peptides.2015 Jun;68:190-6. doi: 10.1016/j.peptides.2015.03.001. PMID: 25784287.

Bucekova, M., Sojka, M., Valachova, I. et al. (2017) Bee-derived antibacterial peptide, defensin-1, promotes wound re-epithelialisation in vitro and in vivo. Sci Rep 7, 7340.

Cornara L, Biagi M, Xiao J, Burlando B. (2017) Therapeutic Properties of Bioactive Compounds from Different Honeybee Products. Front Pharmacol. 2017;8:412. doi:10.3389/fphar.2017.00412

Fujiwara S, Imai J, Fujiwara M, Yaeshima T, Kawashima T, Kobayashi K. A potent antibacterial protein in royal jelly. Purification and determination of the primary structure of royalisin. J BiolChem. 1990 Jul 5;265(19):11333-7. PMID: 2358464.Kwakman PHS, Zaat SAJ. Antibacterial components of honey. IUBMB Life 2012;64:48–55.

Hoffmann, J. A., & Hetru, C. (1992). Insect defensins: inducible antibacterial peptides.Immunology Today, 13(10), 411–415. doi:10.1016/0167-5699(92)90092-l

Kim J, Kim Y, Yun H, Park H, Kim SY, Lee KG, Han SM, Cho Y. (2010) Royal jelly enhances migration of human dermal fibroblasts and alters the levels of cholesterol and sphinganine in an in vitro wound healing model. Nutr Res Pract. 4:362-8. doi: 10.4162/nrp.2010.4.5.362. Epub 2010 Oct 26. PMID: 21103081; PMCID: PMC2981718.

Paredes Barquero, Marta & Niso-Santano, Mireia & Fuentes, Jose & Martínez-Chacón, G. (2022). In vitro and in vivo models to study the biological and pharmacological properties of queen bee acid (QBA, 10-hydroxy-2-decenoic acid): A systematic review. Journal of Functional Foods. 94. 105143. 10.1016/j.jff.2022.105143.

Pasupuleti, V. R., Sammugam, L., Ramesh, N., & Gan, S. H. (2017). Honey, Propolis, and Royal Jelly: A Comprehensive Review of Their Biological Actions and Health Benefits. Oxidative Medicine and Cellular Longevity, 2017, 1–21. doi:10.1155/2017/1259510

Sabatini, Anna & Marcazzan, Gian & Caboni, Maria & Bogdanov, Stefan & Almeida-Muradian,Ligia. (2009). Quality and standardisation of Royal Jelly. Journal of ApiProduct and ApiMedical Science. 1. 1-6. 10.3896/IBRA.4.01.1.04.

DISCLAIMERS
For Topical Use Only, Not Intended for Consumption.

Claims on this page have not been evaluated by the FDA and are not intended to diagnose, cure, treat or prevent any disease.