How it works
- Renew and regenerate skin
- Leaves skin softer, smoother and healthier looking
- Vegan and can be used on people with bee and honey allergies
How to use it
Apply to face, neck and decolletage once or twice daily.
Quick Tips
Ingredients
Water, Glycerin, Lactobacillus/Lactococcus/Leuconostoc/Saccharomyces Laminaria Digitata Ferment Filtrate (and) Algin, Rosa Canina (Rosehip) Seed Oil, Simmondsia Chinensis (Jojoba) Oil, sr-Honey Bee Defensin-1 , sh-Oligopeptide-1, Olea Europaea (Olive) Leaf Extract, Quercetin, Aloe Barbadensis Leaf Extract, Fucoidan, Oryzanol, Hippophae Rhamnoides (Seabuckthorn) Fruit Oil, Dimethicone, Caprylic/Capric Triglyceride, Polyacrylate Crosspolymer-6, Pentylene Glycol, Sucrose Laurate, Propanediol, Ethylhexylglycerin, Benzoic Acid
Research
Bílikova K, Huang SC, Lin IP, Šimuth J, Peng CC. (2015) Structure and antimicrobial activity relationship of royalisin, an antimicrobial peptide from royal jelly of Apis mellifera. Peptides.2015 Jun;68:190-6. doi: 10.1016/j.peptides.2015.03.001. PMID: 25784287.
Bucekova, M., Sojka, M., Valachova, I. et al. (2017) Bee-derived antibacterial peptide, defensin-1, promotes wound re-epithelialisation in vitro and in vivo. Sci Rep 7, 7340.
Cornara L, Biagi M, Xiao J, Burlando B. (2017) Therapeutic Properties of Bioactive Compounds from Different Honeybee Products. Front Pharmacol. 2017;8:412. doi:10.3389/fphar.2017.00412
Fujiwara S, Imai J, Fujiwara M, Yaeshima T, Kawashima T, Kobayashi K. A potent antibacterial protein in royal jelly. Purification and determination of the primary structure of royalisin. J BiolChem. 1990 Jul 5;265(19):11333-7. PMID: 2358464.Kwakman PHS, Zaat SAJ. Antibacterial components of honey. IUBMB Life 2012;64:48–55.
Hoffmann, J. A., & Hetru, C. (1992). Insect defensins: inducible antibacterial peptides.Immunology Today, 13(10), 411–415. doi:10.1016/0167-5699(92)90092-l
Kim J, Kim Y, Yun H, Park H, Kim SY, Lee KG, Han SM, Cho Y. (2010) Royal jelly enhances migration of human dermal fibroblasts and alters the levels of cholesterol and sphinganine in an in vitro wound healing model. Nutr Res Pract. 4:362-8. doi: 10.4162/nrp.2010.4.5.362. Epub 2010 Oct 26. PMID: 21103081; PMCID: PMC2981718.
Paredes Barquero, Marta & Niso-Santano, Mireia & Fuentes, Jose & Martínez-Chacón, G. (2022). In vitro and in vivo models to study the biological and pharmacological properties of queen bee acid (QBA, 10-hydroxy-2-decenoic acid): A systematic review. Journal of Functional Foods. 94. 105143. 10.1016/j.jff.2022.105143.
Pasupuleti, V. R., Sammugam, L., Ramesh, N., & Gan, S. H. (2017). Honey, Propolis, and Royal Jelly: A Comprehensive Review of Their Biological Actions and Health Benefits. Oxidative Medicine and Cellular Longevity, 2017, 1–21. doi:10.1155/2017/1259510
Sabatini, Anna & Marcazzan, Gian & Caboni, Maria & Bogdanov, Stefan & Almeida-Muradian,Ligia. (2009). Quality and standardisation of Royal Jelly. Journal of ApiProduct and ApiMedical Science. 1. 1-6. 10.3896/IBRA.4.01.1.04.
